REGISTRATION 8.30 a.m. – 9.15 a.m. (CEST)
CONFERENCE 9.15 a.m. – 6.00 p.m. (CEST)
| 08:30 – 09:15 | Registration |
| 09:15 – 09:30 | Institutional Greetings |
| 09:30 – 10:45 | Plenary Session Theranostics in Glioblastoma Precision Medicine: The Dark and Bright Sides of the Moon |
| Chair: Concettina La Motta | |
| From Fluorescence-Guided Neurosurgery to Theranostics for High-Grade Gliomas: Clinical and Experimental Examples Lorenzo Magrassi, Neurosurgery, Department of Clinical, Surgical, Diagnostic and Pediatric Science, University of Pavia, Pavia | |
| Targeting ALDH1A3: Drug Discovery Strategies for Next-Generation Theranostics Silvia Garavaglia, Department of Scienze del Farmaco, University of Piemonte Orientale, Novara | |
| Computational Investigation of Benzaldehyde-Based Inhibitors of ALDH1A3 for Theranostic Applications Nicolò Mesano, Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena | |
| 10:45 – 11:15 | Coffee break and Networking |
| Session 1 – Chemical Strategies and Molecular Tools | |
| Chairs: Lorenzo Magrassi and Conxettina La Motta | |
| 11:15 – 11:45 | The Purinergic P2X7 Receptors in Gliomas: Development of Molecular Imaging Tools Enza Lacivita, Department of Pharmacy, Drug Sciences, University of Bari Aldo Moro, Bari |
| 11.45 – 12:00 | Dual Inhibitors of NAMPT and CAs IX and XII: A Multitarget Approach Against Glioblastoma Alessio Nocentini, Department of NEUROFARBA, University of Florence, Florence |
| 12:00 – 12:15 | Development of Peptide Drug Conjugates Targeting the Apelin Receptor for Theranostic Applications Lidia Ciccone, Department of Pharmacy, University of Pisa, Pisa |
| 12:15 – 12:30 | Small Luminescent Molecules: Lighting Up the Way Chiara Gangemi, Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina |
| 12:30 – 12:45 | Fluorescent Ligands for Target Identification and Preclinical Drug Screening in Cancer Maria Majellaro, Celtarys Research SL, Avda., Santiago de Compostela, Spain |
| 12:45 – 14:00 | Lunch break + E-Poster Showcase & Networking |
| Session 2 – Biological Complexity and Clinical Perspectives | |
| Chairs: Silvia Garavaglia and Enza Lacivita | |
| 14:00 – 14:20 | Hadrontherapy: Current Frontiers to Overcome Tumor Radioresistance Angelica Facoetti, Centro Nazionale di Adroterapia Oncologica (CNAO), Pavia |
| 14:20 – 14:40 | Molecular Neuro-Oncology from the Operating Room to the Patient’s Care. Anna Luisa Di Stefano, Dipartimento di Neurochirurgia, Azienda Ospedaliera Toscana Nord-ovest, Livorno |
| 14:40 – 15:00 | Beyond the Loss of Function: PTEN Gain-of-Function Mutations Drive Super-Diffusive Migration and Poor Survival in Glioblastoma Chiara Maria Mazzanti, Fondazione Pisana per la Scienza, Pisa |
| 15:00 – 15:20 | Theranostic Bioimaging Approaches for Glioblastoma: From Surgical Guidance to Immune Monitoring Cristina Chirizzi, Department of Neuroradiology, IRCCS Foundation Neurological Institute “Carlo Besta” |
| 15:20 – 15:40 | Cerebral Open Flow Microperfusion (cOFM) – Interstitial profiling for drug development and precision medicine Thomas Altendorfer-Kroath, HEALTH – Institute for Biomedical Research and Technologies, Joanneum Research Forschungsgesellschaft mbH, Graz, Austria |
| 15:40 – 16:15 | Coffee break and Networking |
| Session 3 – The Youngers’ Point of View | |
| Chairs: Ilaria D’Agostino and Nicolò Messano | |
| 16:15 – 16:30 | Engineered PVA Microbubbles for Targeted Drug Delivery to Glioblastoma Vasculature Alessandra Vitaliti, Department of Chemical Science and Technologies, University of Rome Tor Vergata, Rome, Italy |
| 16:30 – 16:45 | Biomimetic bEnd.3 Membrane-Coated Liposomes for Enhanced Blood–Brain Barrier Targeting Siria Emily Nesti, Department of Pharmacy, University of Pisa, Pisa |
| 16:45– 17:00 | Beyond the brain: circulating tumor cells as a tool for diagnosis and monitoring Francesca Lessi, Fondazione Pisana per la Scienza, Pisa |
| 17:00 – 17:15 | MicroRNAs and Treatment Response in Brain Tumors: Hype, Hope or Clinical Reality? Aleksandar Stepanovic, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia |
| 17:15 – 17:30 | Glucoconjugated Cyclopentadienyl Tricarbonyl Rhenium Complex for Infrared Detection of Glycolytic Cancer Cells Giulia Bononi, Department of Pharmacy, University of Pisa, Pisa |
| 17:30 – 17:45 | AI-Driven Drug Repurposing for Targeted Therapy and Tumor Biology in Glioblastoma Francesca Marchetto, Fondazione Pisana Per La Scienza, Pisa |
| 17:45 – 18:00 | Closing |